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Our 24/7 cancer helpline provides information and answers for people dealing with cancer. We can connect you with trained cancer information specialists who will answer questions about a cancer diagnosis and provide guidance and a compassionate ear.
Live Chat available weekdays, 7:00 am - 6:30 pm CT
Call us at 1-800-227-2345
Available any time of day or night
Our highly trained specialists are available 24/7 via phone and on weekdays can assist through online chat. We connect patients, caregivers, and family members with essential services and resources at every step of their cancer journey. Ask us how you can get involved and support the fight against cancer. Some of the topics we can assist with include:
For medical questions, we encourage you to review our information with your doctor.
Cancer treatments vary from person to person, and everyone's situation is different. Before you choose your treatment plan, it’s important to learn as much as you can.
Ask your cancer care team plenty of questions about your treatment and the expected outcome. Make sure you understand the expected benefits, risks, and side effects.
You will most likely need to give written permission before starting treatment. This is called informed consent. Doctors must get informed consent for many types of treatment. Make sure all your questions are answered before signing the consent form.
The questions below will help you think through your options and choose the best treatment plan.
If surgery is a treatment option for you, consider asking your cancer care team these questions.
If you also plan to have reconstructive surgery, consider asking these additional questions.
Learn more about the role of surgery in cancer treatment.
If chemo is a treatment option for you, consider asking your cancer care team these questions.
Learn more about chemo for cancer treatment.
If radiation is a treatment option for you, consider asking your cancer care team these questions.
Learn more about the role of radiation therapy in cancer treatment.
If targeted therapy is a treatment option for you, consider asking your cancer care team these questions.
Learn more about targeted therapy for cancer treatment.
If immunotherapy is a treatment option for you, consider asking your cancer care team these questions.
Learn more about immunotherapy to treat cancer.
Your regular cancer care team might be able to answer some of your questions about stem cell transplant (SCT). Other questions will best be answered by the specialized team in charge of your transplant.
If a stem cell transplant is a treatment option for you, consider asking these questions.
Learn more about stem cell and bone marrow transplants for cancer treatment.
If hormone therapy is a treatment option for you, consider asking your cancer care team these questions.
Learn more about hormone therapy to treat cancer.
If you want to use supplements or other integrative (holistic) therapies along with your cancer treatment, consider asking your care team these questions.
If you’re thinking of using holistic therapies or supplements instead of traditional treatment, asking these questions can help you make an informed decision.
It’s very important to be honest and open with your cancer care team. They can help you make a safe choice. Keep in mind:
Always talk to your cancer care team before moving ahead.
*Even herbs and vitamins have side effects. If a treatment claims to have no side effects, it most likely hasn’t been studied in rigorous clinical trials, where side effects would be seen.
In the United States, vitamins and supplements aren’t regulated like medicines. They don’t have to be proven effective (or even safe) before being sold.
Learn more about integrative (holistic) medicine.
If a clinical trial is a treatment option for you, consider asking your cancer care team these questions.
Learn more about clinical trials in cancer treatment.
Take notes during your visits. Don’t feel shy about asking them to slow down if you need more time to write.
Ask questions if you don’t understand something. Your cancer care team may draw a picture or give you examples to help you understand.
Ask if you can record the conversation. You can listen to this later if you forget or miss anything.
Bring someone with you. This person can take notes during the visit, help you understand what your care team says, and refresh your memory afterward.
Get contact info. Ask the best way to contact your cancer care team with questions and concerns after the visit. Also ask how to reach someone after office hours.
Developed by the American Cancer Society medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).
American Society of Clinical Oncology. Anesthesia. Cancer.net. Content is no longer available.
American Society of Clinical Oncology. Evaluating integrative, complementary, and alternative therapies. Cancer.net. Content is no longer available.
American Society of Clinical Oncology. Making decisions about cancer treatment. Cancer.net. Content is no longer available.
American Society of Clinical Oncology. Questions to ask about clinical trials. Cancer.net. Content is no longer available.
American Society of Clinical Oncology. Reconstructive surgery. Cancer.net. Content is no longer available.
American Society of Clinical Oncology. Side effects of cancer surgery. Cancer.net. Content is no longer available.
American Society of Clinical Oncology. What are cancer vaccines? Cancer.net. Content is no longer available.
American Society of Clinical Oncology. What is a bone marrow transplant (stem cell transplant)? Cancer.net. Content is no longer available.
American Society of Clinical Oncology. What is cancer surgery? Cancer.net. Content is no longer available.
American Society of Clinical Oncology. What is chemotherapy? Cancer.net. Content is no longer available.
American Society of Clinical Oncology. What is hormone therapy. Cancer.net. Content is no longer available.
American Society of Clinical Oncology. What is targeted therapy? Cancer.net. Content is no longer available.
American Society of Clinical Oncology. What is radiation therapy? Cancer.net. Content is no longer available.
American Society of Clinical Oncology. What to expect when having cancer surgery. Cancer.net. Content is no longer available.
National Cancer Institute (NCI). Questions to ask your doctor about treatment. Updated February 23, 2023. Accessed at https://www.cancer.gov/about-cancer/treatment/questions on May 21, 2025.
Last Revised: August 11, 2025
American Cancer Society medical information is copyrighted material. For reprint requests, please see our Content Usage Policy.
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